• Animal Genome Institute

    The Animal Genome Institute (AGI) is committed to improving the care of animals and their companion humans through genomics research. AGI also strives to train a new generation of scientists interested in genomics.

    AGI is designated as a 501(c)3 non-profit organization by the IRS. AGI is a volunteer-run organization.

     

    We care about animals and their companion humans! ❤

    We find life’s mystery in genomes ❤

    We educate next-generation scientists ❤

  • Projects

     

    Cat IBD

    Current methods of diagnosing IBD (inflammatory bowel disease) in cats are lengthy and often invasive. Early detection of gut inflammation holds a key to preventing and better controlling the disease. BanBan, my fur-ever baby and best friend had suffered from IBD for almost 6 years and crossed the rainbow bridge in 2012. AGI honors BanBan’s life and the love she gave to us and tries to fight IBD.

    Dog Osteosarcoma

    A close friend of mine lost her son to pediatric osteosarcoma, which is a rare and often fatal cancer. Due to the limited cases in humans, research in the diagnosis and treatment of pediatric osteosarcomas is difficult. Previous research has shown that dog osteosarcomas are genetically similar to pediatric osteosarcomas and are much more common. Research in the diagnosis and treatment of dog osteosarcomas will benefit both our canine companions and children suffering from osteosarcoma.

  • Shop Now

    All profits will be donated to the research operation of AGI

    Genomics sample processing

    Genomics sample processing

    $250.00
    Quantity
    Coming soon
    Bioinformatics analysis

    Bioinformatics analysis

    $30.00
    $30 per hour
    Quantity
    Coming soon
  • Please support us!

  • Members

    Scientists and Veterinary Clinitians

    Yuka Imamura, PhD

    Founder & President

    Yuka has more than 20 years of experience in genomics and bioinformatics in both academic and private research institutions (representative papers: Neuron 2009 (PMID: 19477152), PNAS 2011 (PMID: 21368140), Nature 2011 (PMID: 22031440), Science 2018 (PMID: 30545854), Nature Neuroscience 2020 (PMID: 32203497). Being raised on a farm in rural Japan, she has a long-time passion for bettering animal lives and agricultural productivity utilizing her expertise in genomics and bioinformatics and founded Animal Genome Institute (AGI) in 2019. Yuka is trying to support and educate anyone who loves animals and science. For her daytime job, she has spent 9+ years as a faculty member at Penn State University College of Medicine. Now, she enjoys a new role as a bioinformatics scientist at a private company where she works on biomarker science by utilizing machine learning.

    Milena Bogunovic, MD, PhD

    Advisory Board

    Milena is a leading investigator of immunology, now appointed as an Associate Professor at University of Massachusetts Medical School, with a great interest in understanding how coordinated efforts of enteric immune and nervous systems maintain intestinal homeostasis and infection control, and how the dysbiosis in each system may lead to the development of inflammatory gut conditions such as Inflammatory Bowel Diseases (IBD) and Irritable Bowel Syndrome (IBS). She has been a collaborator and a friend of Yuka since she worked as an Assistant Professor at Penn State University College of Medicine and their collaborative paper was recently published in Science Immunology (PMID: 32276965).

    Tomoko Takahashi, PhD, DVM

    Advisory Board

    Tomoko is an Assistant Professor at Laboratory of Veterinary Radiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Japan. Her interest is in radiation therapy for the cancer of cats and dogs. She is also a member of the Veterinary Cancer Society. Not only Tomoko is specialized in cancer therapy in cats and dogs, she sees a broad spectrum of complications in veterinary medicine, including IBD.

    Kazuki Heishima, DVM, PhD, RPS, DJCVP

    Advisory Board

    Kazuki is a researcher of comparative oncology and translational research, appointed as an Assistant Professor at Gifu University, Japan. His research interest is focused on developing novel therapeutic agents and low-invasive biomarkers using miRNAs for human/canine osteosarcoma (PMID: 30683101) and hemangiosarcoma (PMID: 28536479, PMID: 26335793). Kazuki is a collaborator of Yuka, and fully supports her activities.

  • My Blog

    主に備忘録用です

  • Social Feed

    Check out my latest updates!

  • EXPERIENCE

    私の過去の研究遍歴

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    Eurofins Transplant Genomics Inc

     

    Bioinformatics Scientist

    2022 -

     

    民間企業で働きたいと常々思っていたのですが、コロナその他で機が熟し、50前にして転職しました!

     

    フルリモートの解析屋です。研究したことが商品になり患者さんを救う、という点にやりがいを感じてます。

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    Penn State University College of Medicine

    Director, Penn State Hershey Genome Sciences and Bioinformatics Facility

    Associate Professor of Pharmacology, Biochemistry and Molecular Biology

    2013 - 2022

     

    憧れのコアのディレクター職に!

    NGSサンプルプレップから解析まで全部やってました。

     

    苦手なのは請求書の計算と政治。。。(汗)

    Yale University

    Associate Research Scientist

    2009 - 2013

     

    PostDoc

    2005-2008

     

    Program manager for BrainSpan Consortium Project (http://www.brainspan.org/). Studying transcriptional mechanisms involved in human brain development and evolution.

     

    ヒト脳のマイクロアレイ、NGSやってました。ボスは最近ブタ脳を蘇生させて話題になった人。。。

    The Rothberg Institute for Childhood Diseases

    Research Associate

    2008-2009

     

    NGS analysis on childhood disease

     

    NGSの基礎、R&Dラブのメンタリティはここで鍛えて頂きました。

    Howard Hughes Medical Institute, University of Texas Southwestern Medical Center at Dallas - JST ERATO Yanagisawa Orphan Receptor Project

    Postdoctoral Associate

    2001 - 2005

     

    Screening and characterization of natural ligands for orphan G protein-coupled receptors

     

    ダラス&お台場の柳沢正史研でオーファンGPCRのリガンドハンティングしてました。

  • SKILLS

    NGSに関するものなら何でも

    Molecular Biology

    NGSに関わるR&Dなら何でも

    一細胞、FFPEなど、難しいサンプルも承ってます。

    Sequencing

    イルミナを主に使ってます。時々ONT (Oxford Nanopore Technologies)、Ion Torrent、PacBio、新しくBioNanoも導入してます(sequencingというよりはmappingですが)。

    Genomics

    ヒト疾患サンプルが主な対象ですが、基礎研究ものも扱ってます。最近は植物やバクテリアのお客さんも。

    Bioinformatics

    DNA, RNA, epigenome (ChIP-seq, open chromatin, methylation), metagenome, network analysisなどもやってます。下流の解析はR, pythonを使ってます。

    Education

    小2018年からペンステートワールドキャンパス(通信教育)でバイオインフォマティクス1を教えました。医学部では単発講義がメインでしたが、学生以外も対象にNGS解析講習を開きました。

    Entrepreneurship

    念願の猫ウンチプロジェクト、遂に始動!獣医さん兼修士課程の学生さんの学位プロジェクトとしてネズミモデルで始めてます。

     

    Nonprofitの研究所を立ち上げました。動物ゲノム、バイオインフォの普及が主な活動内容です。

  • EDUCATION

    東大に10年いました

     

     

    The University of Tokyo

    Ph.D. Biochemistry and Molecular Biology 1997 – 2001

     

    医学部|清水孝雄研で生理活性脂質;GPCRの研究してました。

     

     

    The University of Tokyo

    B.S., M.Sc. Applied Biochemistry 1991 – 1997

     

    農学部|ノーバケ野口忠研で糖尿病;IGFの研究してました。

  • CONTACT US

    We are currently accepting research analysis requests! We can also provide advice to those who want to study NGS. Please feel free to contact us!

    Animal Genome Institute
    20 N. Palmyra Rd., #505
    Campbelltown PA 17010
    717-454-4211
  • CHECK OUR SNS SITES

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